science
How does the mother’s half-genome merge with father’s half-genome?
The enzyme SPRK1 leads the first step in untangling a sperm's genome, kicking out special packing proteins, which opens up the paternal DNA and allows for major reorganization—all in a matter of hours.
The paternal genome genomes an enormous trade of histone with protamine for compaction into sperm during spermiogenesis. Upon fertilization, this procedure is potently reversed, which is essential for parental genome reprogramming and subsequent activation; h… [+2943 chars]
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